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Whole mounts showing examples of dissected, unfixed, and unstained coagulating glands from a normal prostate from a 23-week-old GEM Nkx3.1+/− × PTEN+/− male (A) and a 23-week-old GEM Nkx3.1−/− × PTEN+/− male with nodular foci of PIN (B). Note the dark masses in B (arrows) that show the areas of cellular proliferation. The bulging profiles of the foci are consistent with GEM PIN III or IV. This type of visualization provides information about the number and volume of the lesions.
