A panel of H&E-stained slides from a Nkx3.1−/− × PTEN+/− mouse with low-magnification images (A, C, E, and G) and higher magnification images (B, D, F, and H) illustrating the histological and cytological patterns of PIN I (A and B), PIN II (C and D), PIN III (E and F), and PIN IV (G and H). These images show the details of the criteria for each grade described in the text. Scale bars document the magnification (G and H).