Table 1.

Effect of EGF on the Amount of Injury Induced by Mesenteric Ischemia and Reperfusion (I + R)

	Control n = 7	Sham operation (laparotomy) n = 10	I + R n = 16	I + R + EGF n = 14
Small intestinal wt (g)	11.61 (11.37–11.89)	11.88 (11.24–12.2)	7.65 (6.6–8.74)	11.50† (11.15–12.15)
Haemoglobin levels in intestinal washout (g/dL)	0 (0–0)	0 (0–0)	2.19 (2.12–3.32)	0† (0–0)
MDA intestine μmol/mg protein	0.29 (0.25–0.35)	0.24 (0.20–0.28)	2.40 (2.20–2.70)	0.71† (0.21–2.00)
MPO intestine U/g tissue	0.24 (0.19, 0.25)	0.20 (0.13, 0.30)	3.15 (2.67, 4.18)	0.20† (0.11–0.55)
MPO lungs U/g tissue	0.22 (0.11, 0.31)	0.21 (0.16, 0.33)	0.76 (0.64, 0.80)	0.30† (0.16–0.35)
MPO kidney U/g tissue	0.14 (0.08–0.20)	0.12 (0.09–0.14)	0.64 (0.47–0.77)	0.30* (0.16–0.35)
Plasma TNF-α pg/mL	<20	57‡ (51–79)	54 (42–67)	22† (<20–36)

MPO, Myeloperoxidase (marker of inflammatory infiltrate); MDA, malondialdehyde levels (free radical marker).

Data are presented as median (interquartile range).

* and ^† indicate P < 0.05 and < 0.01 comparing animals receiving I + R alone against animals also receiving EGF.

^‡ indicates P < 0.01 of sham-operated versus control animals.