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Effect of Intraperitoneal Injection of PAR-2 Agonists on MPO Activity and Microscopic Damage Score (Mean ± SEM; n = 8)
| MPO (U/mg of protein) | Microscopic damage score | |
|---|---|---|
| A | ||
| SLIGRL-NH2 (μg/mice) | ||
| 40 | 201.3 ± 23.1 | 0.5 ± 0.12 |
| 100 | 159.2 ± 12.7 | 0.8 ± 0.10 |
| 400 | 181.2 ± 21.3 | 0.4 ± 0.17 |
| LRGILS-NH2 400 μg | 148.2 ± 30.7 | 0.5 ± 0.23 |
| B | ||
| Time after SLIGRL-NH2 (100 μg/mice) administration | ||
| 4 (h) | 132.1 ± 11.2 | 0.9 ± 0.21 |
| 6 (h) | 155.5 ± 62.74 | 0.5 ± 0.09 |
| 8 (h) | 192.4 ± 36.61 | 0.3 ± 0.06 |
| 10 (h) | 140.9 ± 75.66 | 0.7 ± 0.11 |
