Figure 4.

TGF-β sensitivity of colorectal carcinoma cell lines. Results were normalized and expressed as means ± SE (n = 4) compared to the control (untreated cells). *, P ≤ 0.05 versus control. A: Effect of TGF-β on cell proliferation. The cells were treated with various concentrations of TGF-β for 9 days (for further details see Figure 3A ▶ ). B: Induction of apoptosis measured by flow cytometry. The cells were treated with various concentrations of TGF-β for 48 hours (for further details see Figure 3B ▶ ). C and D: Effect of TGF-β on the expression of CD97. Cells were treated with 0.1 (C) and 1 ng/ml of TGF-β (D) and the expression of CD97 was examined in flow cytometry.