Table 3.
CD97 Expression and Clinicopathological Features
| CD97hom | CD97scatt | P | |
|---|---|---|---|
| Number of cases | 40 | 35 | |
| Age (mean ± SD) | 65.0 ± 10.7 | 65.6 ± 12.0 | |
| Sex | |||
| Male | 23 | 22 | 0.813 |
| Female | 17 | 13 | |
| Tumor location | |||
| Colon | 17 | 17 | 0.647 |
| Rectum | 23 | 18 | |
| Tumor size (pT) | |||
| 1 or 2 | 11 | 5 | 0.258 |
| 3 or 4 | 29 | 30 | |
| Lymph node metastasis (pN) | |||
| 0 | 21 | 11 | 0.801 |
| 1 or 2 | 29 | 24 | |
| Distant metastasis (M) | |||
| 0 | 27 | 20 | 0.473 |
| 1 | 13 | 15 | |
| Tumor stage | |||
| 1 or 2 | 20 | 9 | 0.036* |
| 3 or 4 | 20 | 26 | |
| Differentiation (grade) | |||
| I or II (well, moderate) | 31 | 26 | 0.791 |
| III (poor) | 9 | 9 | |
| Blood vessel invasion | |||
| No (V0) | 26 | 19 | 0.358 |
| Yes (V1) | 14 | 16 | |
| Lymph vessel invasion | |||
| No (L0) | 13 | 4 | 0.050* |
| Yes (L1) | 27 | 31 | |
| Tumor budding | |||
| BD-1 (non/mild) | 16 | 3 | 0.003* |
| BD-2 (moderate/severe) | 24 | 32 |
The CD97-positive carcinomas were subdivided in two groups: carcinomas with homogenous CD97 staining (CD97hom) and carcinomas with stronger stained scattered tumor cells (CD97scatt).
*P ≤ 0.05.