Figure 2.

Preferential localization of S-100⁺ DCs in the granulomatous microstructures. A diagram of the topography of DCs in tissue lesions is shown. S-100⁺ cells were traced and landmarks in the arterial circumference were marked (EEL, external elastic lamina; IEL, internal elastic lamina). Two types of S-100⁺ DC could be distinguished, round lymphoid-like cells (light gray) and spindle-shaped cells with dendrites (dark gray). Both DC types displayed preference for the media and were in close association with granulomatous reactions.