Table 4B.
Genes Down-Regulated by Chronic LPS-Challenge
| Group | Abbreviation | Name | GenBank | Saline/LPS |
|---|---|---|---|---|
| Apoptosis | CLU | clusterin precursor | L08235 | 5.0 |
| Apoptosis | CPR | NADPH-cytochrome P450 reductase | D17571 | 3.7 |
| Basic Transcription Factors | NKX-2.6 | Drosophila NK2 transcription factor-related locus 6 | AF030113 | 4.3 |
| Basic Transcription Factors | HFH-4 | hepatocyte nuclear factor 3 | L13204 | 3.4 |
| Basic Transcription Factors | SOX13 | HMG-box transcription factor | AJ000740 | 4.0 |
| Basic Transcription Factors | TF II D | transcription initiation factor TF II D | D01034 | 3.0 |
| Basic Transcription Factors | GLI2 | zinc finger protein | X99104 | 4.6 |
| Cell-Cell Adhesion Receptors | ADAM8 | cell surface antigen MS2 | D10911 | 4.1 |
| Cell-Cell Adhesion Receptors | EPHA6 | ephrin type A R 6 | U58332 | 5.3 |
| Cell-Cell Adhesion Receptors | CD14 | CD14 | M34510 | 4.3 |
| Cell-Cell Adhesion Receptors | integrin alpha 7 | integrin alpha 7 | L23423 | 4.4 |
| Cyclins | cyclin T1 | cyclin T1 | AF109179 | 3.7 |
| Cyclins | CCNE2 | G1/S-specific cyclin E2 | AF091432 | 3.1 |
| Cytoskeleton & Motility | LAMC2 | laminin gamma 2 subunit precursor | U43327 | 4.4 |
| Cytoskeleton & Motility | talin | talin | X56123 | 3.5 |
| DNA Damage/Repair | CTCBF | ATP-dependent DNA helicase II 70-kDa subunit | M38700 | 3.1 |
| Growth Factor & Chemokine Receptors | PDGF | pre-platelet-derived growth factor R | X04367 | 6.0 |
| Growth Factors and Cytokines | VGR1 | bone morphogenetic protein 6 precursor | X80992 | 4.0 |
| Growth Factors and Cytokines | CERR1 | cerberus-related protein1 | AF031896 | 4.1 |
| Growth Factors and Cytokines | Mdkk1 | dickkopf homolog 1 | AF030433 | 3.8 |
| Growth Factors and Cytokines | GCSF | granulocyte colony-stimulating factor | M13926 | 5.1 |
| Growth Factors and Cytokines | GDF9 | growth differentiation factor 9 | X77113 | 3.0 |
| Growth Factors and Cytokines | HBGF5 | heparin-binding growth factor 5 precursor | M30643 | 4.1 |
| Growth Factors and Cytokines | LIF | leukemia inhibitory factor | X06381 | 3.7 |
| Growth Factors and Cytokines | SHH | sonic hedgehog homolog | X76290 | 3.4 |
| Intracellular Adaptors | PTPN11 | non-receptor type 11 protein tyrosine phosphatase | D84372 | 4.2 |
| Intracellular Adaptors | Sik | Src-related intestinal kinase | U16805 | 4.6 |
| Intracellular Kinase | S6KII-alpha | ribosomal protein S6 kinase II alpha 1 | M28489 | 3.4 |
| Intracellular Transducers | B-50 | neuromodulin | J02809 | 3.7 |
| Intracellular Transducers | TLL | tolloid-like protein | U34042 | 3.6 |
| Ion Channels (Voltage-Gated) | SODIUM CH | voltage-gated sodium channel | L36179 | 4.6 |
| Oncogenes & Tumor Suppressors | c-fos | c-fos | V00727 | 5.5 |
| Oncogenes & Tumor Suppressors | c-Src | c-Src | M17031 | 3.4 |
| Oncogenes & Tumor Suppressors | ERP | ets-domain protein elk3 | Z32815 | 4.8 |
| Oncogenes & Tumor Suppressors | G-protein R 27 | G-protein coupled receptor 27 | U79525 | 3.9 |
| Oncogenes & Tumor Suppressors | R-ras | R-ras protein | M21019 | 4.8 |
| Oncogenes & Tumor Suppressors | MMP11 | matrix metalloproteinase 11 | Z12604 | 3.5 |
| Oncogenes & Tumor Suppressors | TSG101 | tumor susceptibility protein 101 | U52945 | 3.4 |
| Oncogenes & Tumor Suppressors | Vav | GDP-GTP exchange factor | X64361 | 7.0 |
| Recombination Proteins | RAG2 | V(D)J recombination activating protein | M64796 | 3.6 |
| Transcription Activators & Repressors | ATOH2 | atonal protein homolog 2 | U29086 | 3.4 |
| Transcription Activators & Repressors | IRF1 | interferon regulatory factor 1 | M21065 | 3.0 |
| Transcription Activators & Repressors | mf 5 | myogenic factor 5 | X56182 | 3.9 |
| Transcription Activators & Repressors | PSD-95 | PSD-95/SAP90A | D50621 | 3.0 |
| Transcription Activators & Repressors | STAT1 | STAT1 | U06924 | 4.2 |
| Unclassified Proteins | FMR2 | fragile X mental retardation syndrome | AJ001549 | 3.5 |
| Unclassified Proteins | HUD | Huntington disease homolog | U24233 | 7.6 |
| Unclassified Proteins | HAP1 | huntingtin-associated protein 1 | AJ000262 | 4.6 |
| Unclassified Proteins | petaxin-related | petaxin-related C-reactive protein | X13588 | 3.4 |
| Unclassified Proteins | PS1 | presenilin-1 | AF007560 | 4.6 |
| Unclassified Proteins | tubby | tubby | U54643 | 3.6 |
| Unclassified Proteins | WSB1 | WSB1 protein | AF033186 | 4.2 |