Table 6A.
Supplemental Table 2A ▶ .
Genes Down-Regulated by Antigen-Induced Bladder Inflammation
| Group | Abbreviation | Gene | GenBank | AG | SP | LPS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 4 | 24 | 1 | 4 | 24 | 1 | 4 | 24 | ||||
| Adhesion | EPOR | erythropoietin receptor precursor | J04843 | 3 | 2 | 1 | 2 | 3 | 2 | 1 | 1 | 1 |
| Apoptosis | nur77 | early response protein; nuclear hormone receptor | J04113 | 4 | 1 | 1 | 2 | 1 | 2 | 2 | 0 | 1 |
| Basic Transcription Factors | HOX-4.5 | Homeobox Protein 4.5 | S94664 | 2 | 8 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
| Basic Transcription Factors | HOX10 | homeobox protein 10 | L34808 | 1 | 4 | 1 | 2 | 1 | 2 | 1 | 2 | 1 |
| Basic Transcription Factors | NAB1 | transcription repressor | U47008 | 1 | 3 | 0 | 2 | 2 | 1 | 2 | 1 | 1 |
| Basic Transcription Factors | HHEX | hematopoietically expressed homeobox protein | Z21524 | 3 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 |
| Bcl Family Proteins | BAK1 | bcl-2 homologous antagonist/killer | Y13231 | 3 | 2 | 1 | 2 | 1 | 1 | 2 | 0 | 1 |
| Caspases | ICE | interleukin-converting enzyme | L28095 | 4 | 1 | 1 | 3 | 1 | 1 | 3 | 1 | 1 |
| Cell-Cell Adhesion Receptors | N-cadherin | neural cadherin precursor | M31131 | 3 | 1 | 1 | 3 | 1 | 1 | 2 | 2 | 1 |
| Complement Receptors | C5A receptor R | C5A receptor | L05630 | 3 | 1 | 1 | 2 | 1 | 1 | 3 | 0 | 1 |
| Cytoskeleton & Motility | COL10A1 | collagen 10 alpha 1 | X67348 | 3 | 4 | 1 | 2 | 2 | 1 | 1 | 2 | 1 |
| Cytoskeleton & Motility | MLC3NM | non-muscle myosin light chain 3 | U04443 | 6 | 5 | 2 | 3 | 2 | 1 | 1 | 2 | 2 |
| Cytoskeleton & Motility | unconventional myosin | unconventional myosin VI | U49739 | 3 | 4 | 1 | 2 | 3 | 1 | 1 | 1 | 2 |
| Death Kinases | RAC-PK-alpha | serine/threonine kinase | M94335 | 4 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 |
| DNA Damage/Repair | XPAC | xeroderma pigmentosum group A correcting protein | X74351 | 3 | 3 | 1 | 2 | 2 | 1 | 2 | 2 | 1 |
| DNA Damage/Repair | Ung1 | uracil-DNA glycosylase | X99018 | 3 | 3 | 1 | 2 | 1 | 1 | 2 | 2 | 1 |
| DNA Damage/Repair | HR21spA | protein involved in DNA double-strand break repair | D49429 | 3 | 5 | 0 | 1 | 2 | 1 | 1 | 2 | 1 |
| DNA Damage/Repair | ERCC1 | DNA excision repair protein | X07414 | 5 | 5 | 1 | 2 | 2 | 1 | 2 | 2 | 2 |
| Growth Factor & Chemokine Receptors | C-C chemokine R 1 | monocyte chemoattractant protein 1 receptor | U56819 | 3 | 1 | 1 | 2 | 1 | 2 | 1 | 0 | 1 |
| Heat Shock Proteins | MTJ1 | DNAJ-like heat-shock protein from mouse tumor | L16953 | 1 | 3 | 1 | 0 | 2 | 2 | 0 | 0 | 1 |
| Heat Shock Proteins | HSP84 | 84-kDa heat shock protein | M36829 | 1 | 3 | 0 | 1 | 2 | 1 | 0 | 1 | 2 |
| Hormone Receptors | somatostatin R 2 | somatostatin receptor 2 | M81832 | 3 | 1 | 1 | 3 | 2 | 1 | 3 | 2 | 1 |
| Prostaglandin Receptors | prostaglandin I R | prostaglandin I receptor (IP) | D26157 | 2 | 4 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
| Neurotransmitter Receptors | acetylcholine R alpha 7 | acetylcholine receptor alpha 7 neural | L37663 | 2 | 3 | 1 | 2 | 2 | 1 | 2 | 3 | 1 |
| Nucleotide Metabolism | HDC | histidine decarboxylase | X57437 | 3 | 3 | 1 | 2 | 2 | 1 | 1 | 1 | 1 |
| Oncogenes & Tumor Suppressors | Gli | Gli oncogene; zinc finger transcription factor | S65038 | 1 | 4 | 1 | 1 | 2 | 1 | 1 | 2 | 1 |
| Oncogenes & Tumor Suppressors | fos-L2 | fos-related antigen 2 | X83971 | 1 | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Oncogenes & Tumor Suppressors | NDK B | nucleoside diphosphate kinase B | X68193 | 1 | 4 | 1 | 1 | 2 | 1 | 0 | 0 | 1 |
| Oncogenes & Tumor Suppressors | c-Cbl | c-Cbl proto-oncogene | X57111 | 2 | 5 | 1 | 2 | 3 | 1 | 1 | 2 | 1 |
| Oncogenes & Tumor Suppressors | c-Fgr | c-Fgr proto-oncogene | X52191 | 2 | 5 | 0 | 1 | 3 | 1 | 1 | 1 | 2 |
| Ribosomal Proteins | LAMR1 | lamimin receptor 1 | J02870 | 1 | 4 | 1 | 1 | 3 | 1 | 1 | 2 | 1 |
| Symporters & Antiporters | VAT-1 | Synaptic membrane protein | X95562 | 1 | 5 | 0 | 1 | 3 | 1 | 1 | 1 | 1 |
| Transcription Activators & Repressors | BARX1 | homeodian transcription factor | Y07960 | 5 | 10 | 1 | 1 | 2 | 1 | 1 | 2 | 1 |
| Transcription Activators & Repressors | OCT6 | octamer-binding transcription factor 6 | X56959 | 4 | 6 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
| Transcription Activators & Repressors | RXR gamma | retinoic acid receptor gamma | M84819 | 1 | 3 | 1 | 1 | 3 | 0 | 1 | 1 | 1 |
| Transcription Activators & Repressors | Stat6 | signal transducer and activator of transcription 6 | L47650 | 5 | 3 | 1 | 1 | 2 | 0 | 1 | 2 | 1 |
| Transcription Activators & Repressors | EED | embryonic ectoderm development protein | U78103 | 1 | 3 | 1 | 1 | 2 | 1 | 1 | 1 | 1 |
| Unclassified Proteins | FMN | formin | X53599 | 2 | 4 | 1 | 2 | 2 | 1 | 1 | 1 | 1 |
| Unclassified Proteins | KL | klotho protein | AB005141 | 1 | 3 | 1 | 2 | 1 | 1 | 0 | 1 | 1 |
| Unclassified Proteins | COBL | cordon-bleu protein | U26967 | 2 | 3 | 1 | 2 | 2 | 1 | 1 | 2 | 1 |
| Unclassified Proteins | FBN1 | fibrillin 1 precursor | L29454 | 3 | 3 | 1 | 2 | 2 | 1 | 1 | 2 | 2 |
| Xenobiotic Transporters | GPX3 | plasma glutathione peroxidase precursor | U13705 | 2 | 3 | 1 | 1 | 3 | 1 | 1 | 1 | 1 |
Ratio of Gene Expression (Treatment/Saline) was calculated from individual expressions as % of beta-actin.
Numbers in bold indicate peak of gene expression.