Table 6C.
Supplemental Table 2C ▶ .
Genes Down-Regulated by LPS-Induced Bladder Inflammation
| Group | Abbreviation | Gene | GenBank | AG | SP | LPS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 4 | 24 | 1 | 4 | 24 | 1 | 4 | 24 | ||||
| ABC Transporters | ABC8 | ATP-binding casette 8 | U34920 | 0 | 1 | 0 | 2 | 2 | 1 | 1 | 1 | 4 |
| Adhesion | semophorin J | semaphorin J | U69535 | 2 | 2 | 1 | 3 | 1 | 0 | 7 | 2 | 1 |
| Basic Transcription Factors | JUMONJI | Jumonji protein | D31967 | 1 | 2 | 0 | 1 | 2 | 0 | 4 | 7 | 1 |
| Basic Transcription Factors | PMX2 | paired mesoderm homeobox protein 2 | X52875 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 |
| Basic Transcription Factors | RPX | anterior-restricted homeobox | X80040 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 5 | 1 |
| Caspases | CASP2 | caspase-2 precursor | D28492 | 2 | 1 | 1 | 2 | 1 | 2 | 4 | 0 | 1 |
| Cyclins | CCNB2 | G2/M-specific cyclin B2 | X66032 | 1 | 3 | 1 | 2 | 2 | 1 | 2 | 4 | 3 |
| Death Receptors | adenosine A3 R | adenosine A3 receptor | L20331 | 1 | 1 | 0 | 3 | 2 | 1 | 3 | 1 | 1 |
| DNA Damage/Repair | MmRad52 | DNA repair protein Rad52 homolog | Z32767 | 2 | 2 | 1 | 2 | 1 | 1 | 0 | 3 | 2 |
| DNA Damage/Repair | MmMre11a | putative endo/exonuclease | U58987 | 2 | 2 | 1 | 2 | 1 | 1 | 3 | 4 | 1 |
| G Proteins | E13g | guanine nucleotide binding protein | M36777 | 1 | 1 | 1 | 1 | 2 | 1 | 3 | 6 | 3 |
| Growth Factors and Cytokines | GPI | glucose-6-phosphate isomerase | M14220 | 3 | 1 | 1 | 2 | 1 | 1 | 3 | 1 | 1 |
| Growth Factors and Cytokines | FGF14 | fibroblast growth factor 14 | U66204 | 1 | 1 | 0 | 2 | 1 | 1 | 3 | 1 | 1 |
| Hormone Receptors | VIP R 2 | vasoactive intestinal peptide receptor 2 | D28132 | 0 | 2 | 0 | 1 | 3 | 1 | 4 | 3 | 1 |
| Hormone Receptors | oxytocin R | oxytocin receptor | D86599 | 1 | 2 | 0 | 2 | 2 | 1 | 4 | 2 | 3 |
| Hormone Receptors | androgen R | androgen receptor | X53779 | 1 | 1 | 0 | 3 | 1 | 1 | 3 | 0 | 1 |
| Hormones | CRH binding protein | corticotropin releasing hormone binding protein | U33323 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 6 | 1 |
| Interleukin & Interferon Receptors | IL-7R alpha | interleukin-7 receptor alpha | M29697 | 2 | 2 | 0 | 3 | 2 | 0 | 3 | 1 | 1 |
| Interleukins & Interferons | IFN-BETA | Interferon beta precursor | K00020 | 2 | 3 | 1 | 2 | 2 | 0 | 3 | 1 | 1 |
| Ion Channels (Ligand-Gated) | KVLQT1 | voltage-gated potassium channel protein KQT-like 1 | U70068 | 0 | 1 | 0 | 1 | 2 | 1 | 1 | 1 | 5 |
| Metalloproteinases | MMENDO | membrane metallo endopeptidase | M81591 | 2 | 2 | 1 | 3 | 2 | 1 | 1 | 4 | 1 |
| Neurotransmitter Receptors | glutamate R delta 1 | glutamate receptor, ionotropic, delta 1 | D10171 | 1 | 2 | 0 | 2 | 3 | 1 | 4 | 3 | 3 |
| Neurotransmitter Receptors | GRP R | gastrin releasing peptide receptor | M57922 | 1 | 1 | 0 | 2 | 1 | 1 | 2 | 3 | 2 |
| Neurotransmitter Receptors | 5-HT 2c | 5-hydroxytryptamine receptor 2c | Z15119 | 1 | 1 | 1 | 2 | 1 | 1 | 4 | 1 | 1 |
| Oncogenes & Tumor Suppressors | RB1 | retinoblastoma-associated protein 1 | M26391 | 1 | 1 | 0 | 2 | 2 | 1 | 2 | 2 | 3 |
| Oncogenes & Tumor Suppressors | HRA | thyroid hormone receptor alpha 1 | X51983 | 1 | 2 | 1 | 2 | 2 | 1 | 3 | 5 | 2 |
| Transcription Activators & Repressors | DLK | delta-like protein precursor | L12721 | 1 | 1 | 0 | 2 | 1 | 1 | 2 | 3 | 2 |
| Transcription Activators & Repressors | DBP | D-binding protein | U29762 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 4 |
| Transcription Activators & Repressors | CTCF | transcription factor CTCF (11 zinc fingers) | U51037 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 3 | 1 |
| Transcription Activators & Repressors | Hox-3.1 | homeobox protein 3.1 | X07439 | 1 | 2 | 1 | 2 | 2 | 1 | 2 | 8 | 1 |
| Transcription Activators & Repressors | Hox-8 | homeobox protein 8 | X59252 | 0 | 0 | 0 | 2 | 2 | 0 | 4 | 1 | 3 |
| Unclassified Proteins | DGCR6 | DiGeorge syndrome chromosome region 6 protein | AF021031 | 0 | 1 | 1 | 2 | 3 | 1 | 1 | 2 | 3 |
| Unclassified Proteins | LEP | leptin precursor | U22421 | 1 | 2 | 1 | 3 | 2 | 1 | 1 | 4 | 2 |
| Xenobiotic Transporters | glutathione reductase | glutathione reductase | X76341 | 0 | 2 | 0 | 0 | 1 | 1 | 0 | 1 | 3 |
Ratio of Gene Expression (Treatment/Saline) was calculated from individual expressions as % of beta-actin.
Numbers in bold indicate peak of gene expression.