Table 7C.
Supplemental Table 3C ▶ .
Genes Up-Regulated by LPS-Induced Bladder Inflammation
| Group | Abbreviation | Gene | GenBank | Antigen | Substance P | LPS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 4 | 24 | 1 | 4 | 24 | 1 | 4 | 24 | ||||
| ABC Transporters | ABC8 | ATP-binding casette 8 | U34920 | 0.5 | 1.2 | 0.5 | 0.5 | 2.8 | 1.0 | 0.4 | 6.1 | 1.0 |
| Apoptosis | GADD45 | GADD45 | L28177 | 0.2 | 1.1 | 1.8 | 0.2 | 0.6 | 1.3 | 0.7 | 4.1 | 1.4 |
| Basic Transcription Factors | Act 2 | macrophage inflammatory protein 1 beta | M35590 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 4.8 | 5.2 | 1.0 |
| CDK Inhibitors | p19ink4 | cdk4 and cdk6 inhibitor | U19597 | 0.3 | 2.4 | 1.0 | 0.4 | 0.6 | 1.0 | 1.0 | 4.1 | 1.0 |
| Cell Cycle Proteins | Cdc25a | M-phase inducer phosphatase 1 | U27323 | 1.0 | 1.9 | 2.0 | 0.3 | 0.7 | 2.4 | 1.0 | 1.3 | 4.0 |
| Cell-Cell Adhesion Receptors | CD14 | LPS receptor | M34510 | 1.0 | 0.4 | 1.6 | 0.8 | 0.7 | 1.4 | 3.2 | 1.0 | 0.4 |
| Cell-Cell Adhesion Receptors | desmocollin 2 | desmocollin 2 | L33779 | 0.9 | 0.9 | 2.5 | 1.0 | 0.8 | 0.3 | 0.3 | 6.9 | 1.0 |
| Cell-Cell Adhesion Receptors | integrin alpha 7 | integrin alpha 7 | L23423 | 1.9 | 1.9 | 1.3 | 0.6 | 0.8 | 1.8 | 2.3 | 4.1 | 3.7 |
| Cytoskeleton & Motility | TUBB4 | tubulin beta 4 | M28730 | 1.5 | 2.3 | 1.1 | 0.5 | 2.3 | 1.1 | 1.5 | 4.7 | 2.7 |
| Death Receptor Ligands | FASL | fas antigen ligand; TNFSF6 | U06948 | 0.3 | 1.0 | 0.3 | 0.5 | 1.3 | 1.0 | 0.4 | 4.8 | 1.0 |
| Death Receptors | beta2-RAR | retinoic acid receptor beta-2 | S56660 | 0.7 | 1.2 | 0.3 | 0.6 | 2.6 | 1.0 | 1.0 | 4.0 | 1.0 |
| DNA Damage/Repair | FACC | Fanconi anemia group C | L08266 | 2.0 | 0.8 | 1.0 | 0.6 | 1.4 | 0.8 | 5.1 | 1.7 | 2.6 |
| DNA Damage/Repair | POLA | DNA polymerase alpha | D17384 | 1.8 | 0.8 | 2.3 | 0.5 | 1.1 | 0.6 | 4.8 | 1.3 | 2.3 |
| DNA Damage/Repair | RAD51 | DNA repair protein RAD51 homolog 1 | D13473 | 1.0 | 0.8 | 2.0 | 0.4 | 0.4 | 0.8 | 5.1 | 2.9 | 1.6 |
| Extracellular Transporters | TBPA | transthyretin precursor | D89076 | 0.5 | 0.7 | 1.1 | 0.3 | 0.9 | 0.5 | 0.8 | 5.1 | 1.0 |
| Fatty Acid Metabolism | FAAH | fatty acid amide hydrolase | U82536 | 0.3 | 1.2 | 1.1 | 0.5 | 1.8 | 1.5 | 0.6 | 5.1 | 2.8 |
| Interleukins & Interferons | IL-6 | Interleukin-6 precursor | X06203 | 1.0 | 1.0 | 1.0 | 2.4 | 1.0 | 1.0 | 11.7 | 3.7 | 1.0 |
| Intracellular Transducers | SOCS2 | cytokine inducible SH2 | U88327 | 1.9 | 0.7 | 2.0 | 0.9 | 0.5 | 1.2 | 4.2 | 1.0 | 2.3 |
| Ion Channels (Membrane) | SCF 1-7 | solute carrier family 1, member 7 | L42115 | 0.3 | 2.8 | 1.0 | 0.5 | 2.8 | 1.0 | 0.5 | 5.4 | 1.0 |
| Ion Channels (Membrane) | QT | QT potassium channel | U04294 | 0.4 | 0.9 | 0.6 | 0.8 | 1.5 | 1.0 | 0.3 | 4.9 | 1.0 |
| Ion Channels (Membrane) | SCF 1-6 | solute carrier family 1, member 6 | D83262 | 0.3 | 2.5 | 1.0 | 0.7 | 2.5 | 1.0 | 0.7 | 4.6 | 1.0 |
| Oncogenes & Tumor Suppressors | c-jun | transcription factor AP-1 | J04115 | 0.8 | 0.3 | 1.0 | 1.8 | 0.7 | 1.1 | 6.8 | 2.6 | 0.4 |
| Oncogenes & Tumor Suppressors | INI1A | integrase interactor 1A protein | AJ011739 | 1.0 | 2.2 | 0.9 | 0.3 | 0.9 | 0.4 | 1.0 | 4.8 | 1.0 |
| Oncogenes & Tumor Suppressors | c-rel | c-rel | X15842 | 0.5 | 2.7 | 1.0 | 0.3 | 2.7 | 1.0 | 1.0 | 4.7 | 1.0 |
| Oncogenes & Tumor Suppressors | abl | abl | L10656 | 0.6 | 1.2 | 1.5 | 0.3 | 2.1 | 1.9 | 0.8 | 4.0 | 2.1 |
| Symporters & Antiporters | SYTIII | synaptotagmin III | D45858 | 0.5 | 1.1 | 1.0 | 0.6 | 1.0 | 1.0 | 0.6 | 5.4 | 1.0 |
| Transcription Activators & Repressors | Pml | murine homolog of the leukemia | U33626 | 0.5 | 2.7 | 1.0 | 1.0 | 2.7 | 0.3 | 1.0 | 5.6 | 1.0 |
| Transcription Activators & Repressors | E2F-3 | transcription factor E\ | AF015948 | 2.0 | 1.3 | 2.2 | 2.4 | 0.6 | 1.7 | 2.4 | 2.3 | 4.0 |
| Unclassified Proteins | WSB1 | WSB1 protein | AF033186 | 2.1 | 1.5 | 1.5 | 2.3 | 2.5 | 1.1 | 14.9 | 13.4 | 1.5 |
| Unclassified Proteins | frataxin | Friedreich ataxia protein | U95736 | 1.6 | 0.4 | 1.8 | 0.9 | 0.5 | 1.1 | 13.9 | 2.2 | 1.8 |
| Unclassified Proteins | huntingtin | Huntington disease homolog | U24233 | 1.8 | 0.9 | 0.5 | 0.5 | 1.2 | 0.7 | 12.5 | 5.2 | 1.9 |
| Unclassified Proteins | NGF-I | NGF-inducible protein TIS21 | M64292 | 0.8 | 0.7 | 1.2 | 2.2 | 0.6 | 1.1 | 11.3 | 1.6 | 0.3 |
| Unclassified Proteins | LEP | leptin precursor | U22421 | 1.2 | 0.7 | 2.0 | 1.8 | 0.3 | 2.6 | 9.4 | 0.7 | 2.6 |
| Unclassified Proteins | tubby | tubby | U54643 | 1.6 | 0.9 | 2.3 | 1.0 | 0.4 | 1.1 | 8.0 | 2.0 | 1.1 |
| Unclassified Proteins | COBL | cordon-bleu protein | U26967 | 0.9 | 0.5 | 1.8 | 0.5 | 0.5 | 0.8 | 7.0 | 0.5 | 1.8 |
| Unclassified Proteins | petaxin | petaxin-related C-reactive protein | X13588 | 0.9 | 0.7 | 1.8 | 0.4 | 0.6 | 1.3 | 5.9 | 1.6 | 1.7 |
| Unclassified Proteins | KL | klotho protein | AB005141 | 0.3 | 0.8 | 2.0 | 0.8 | 0.4 | 1.2 | 5.8 | 1.2 | 2.0 |
| Unclassified Proteins | PPEF2 | protein phosphatase with EF-hands 2 | AF023458 | 1.4 | 0.7 | 1.3 | 1.7 | 0.4 | 0.9 | 5.4 | 1.3 | 2.9 |
| Unclassified Proteins | ajuba | ajuba protein | U79776 | 0.8 | 0.7 | 1.5 | 0.4 | 0.3 | 1.3 | 4.2 | 0.9 | 1.3 |
| Xenobiotic Transporters | HO-2 | Heme oxygenase | AF029874 | 0.9 | 0.4 | 1.8 | 0.9 | 0.5 | 2.0 | 0.9 | 2.1 | 4.0 |
Ratio of Gene Expression (Treatment/Saline) was calculated from individual expressions as % of beta-actin.
Numbers in bold indicate peak of gene expression.