Table 5.
Comparison of Microdissected Tumor Epithelial Areas with Microdissected Normal Epithelial Areas
| Accession no.* | Description | Fold change† TE/NE1 | Fold change‡ TE/NE2 |
|---|---|---|---|
| Overexpressed genes | |||
| X96584 | NOV (nephroblastoma overexpressed gene) | 63.4 | 16.6 |
| M94856 | Fatty acid binding protein 5 | 42.1 | 28.6 |
| M21535 | Transcriptional regulator ERG | 35.5 | 35.5 |
| U21128 | Lumican | 34.7 | 18.1 |
| J03870 | Cystatin SN | 26.2 | 25.6 |
| AL049977 | Claudin 8 | 24.7 | 24.6 |
| X94323 | Specific granule protein (SGP28) | 20.0 | 19.1 |
| X07820 | Matrix metalloproteinase 10 (stromelysin 2) | 19.6 | 18.5 |
| AJ006835 | RNU17D | 17.8 | 18.5 |
| AF053356 | Clone | 17.3 | 16.7 |
| Underexpressed genes | |||
| U95626 | Chemokine receptor 2 | −128.1 | −42.8 |
| AF022991 | Periodic circadian protein 1 (RIGUI) | −54.0 | −70.6 |
| AB006532 | RecQ protein-like 4 | −42.2 | −18.2 |
| Z49878 | Guanidinoacetate N-methyltransferase | −30.9 | −19.2 |
| AB018278 | Synaptic vesicle protein 2B homolog | −20.9 | −15.5 |
| M21389 | Keratin 5 | −19.3 | −17.4 |
| U17760 | Laminin, beta 3 | −18.6 | −19.7 |
| AJ238246 | Keratin 7 (sarcolectin) | −15.2 | −18.9 |
| AF085807 | Uroplakin IA | −15.0 | −15.3 |
*GenBank accession number.
†Fold change represents mRNAs differentially over- or underexpressed in microdissected tumor epithelium (TE) relative to microdissected normal epithelium (NE1, NE2). Only fold differences >15 were taken into consideration.
‡Fold change was calculated by Affymetrix software.