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. 2002 Jun;160(6):1945–1951. doi: 10.1016/S0002-9440(10)61143-1

Figure 3.

Figure 3.

Differential expression of GATA-3 in cervical (pre)malignant lesions. Immunohistochemical detection of GATA-3 in normal cervical squamous epithelium (a, b), CIN I lesions (c, d), CIN III lesions (e, f), cervical carcinomas (g, i, k, l), and Ki-67/MIB1 in cervical carcinomas (h, j). a and b: GATA-3 is expressed in nuclei of basal and parabasal cells of normal cervical epithelium. c and d: CIN I: GATA-3 expression is found in basal, parabasal, and more differentiated cells of cervical epithelium. e and f: CIN III: GATA-3 is weakly expressed in basal and upper layers of cervical epithelium. g: Cervical squamous cell carcinoma: GATA-3 expression is focal and weak in tumor areas. h: Consecutive section of g, showing strong staining for Ki-67/MIB-1 in tumor areas. i: Cervical squamous cell carcinoma: GATA-3 staining is absent in tumor areas. j: Consecutive section of i, showing strong staining for Ki-67/MIB-1 in tumor areas. k and l: Cervical squamous cell carcinomas: GATA-3 staining is absent in tumor areas, whereas lymphocytes stain positive.