Table 3.
Synergistic Effect between ANXA10 Down-Regulation and p53 Mutation in Unifocal Hepatocellular Carcinoma
| Feature | Down-Regulation of ANXA10/p53 mutation | P value | |||
|---|---|---|---|---|---|
| No/No n = 33 | Yes/No n = 46 | No/Yes n = 19 | Yes/Yes n = 58 | ||
| Tumor grade | |||||
| I | 16 (48%) | 9 (20%) | 4 (21%) | 4 (7%) | <0.00001 |
| II–III | 17 | 37 | 15 | 54 | |
| Tumor stage | |||||
| I–II | 26 (79%) | 23 (50%) | 10 (53%) | 13 (22%) | <0.00001 |
| III–IV | 8 | 23 | 9 | 45 | |
| Early intrahepatic tumor recurrence* | 7/30 (23%) | 15/38 (39%) | 6/15 (40%) | 36/53 (68%) | 0.0001 |
*Tumor recurs in the liver ≤12 months after resection of the primary HCC.