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. 2002 May;160(5):1857–1865. doi: 10.1016/S0002-9440(10)61132-7

Table 5.

Summary of the mtDNA Somatic Point Mutations in Coding Genes of the OXPHOS System in Non-Hürthle and Hürthle Cell Tumors

Diagnosis CpI CpIII CpIV CpV
Total point mutations
    Non-Hürthle 8/26 (30.8%) P = 0.607 2/26 (7.7%) P = 0.322 5/26 (19.2%) P = 0.751 1/26 (3.8%) P = 0.232
    Hürthle 10/40 (25.0%) 1/40 (2.5%) 9/40 (22.5%) 5/40 (12.5%)
Missense point mutations
    Non-Hürthle 4/26 (15.4%) P = 0.966 1/26 (3.8%) P = 0.755 2/26 (7.7%) P = 0.535 0/26 (0.0%) P = 0.096
    Hürthle 6/40 (15.0%) 1/40 (2.5%) 5/40 (12.5%) 4/40 (10.0%)

Cp, Complex of the OXPHOS system.