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. 2002 Dec;161(6):2179–2193. doi: 10.1016/s0002-9440(10)64495-1

Figure 8.

Figure 8.

Glomerular TGF-β1 up-regulation in RMR and effect of ACE inhibitor. TGF-β1 mRNA expression by in situ hybridization in glomeruli of a, sham control revealing weak signal in podocytes, b, RMR at 7 days; c, RMR at 14 days; d, RMR at 30 days; e, RMR at 30 days plus ACE inhibitor. TGF-β1 mRNA signal is increased in RMR at 14 days (c) in podocytes (arrows) and intracapillary areas, and it becomes more diffuse at 30 days (d). The ACE inhibitor prevents TGF-β1 up-regulation (e). f, RMR at 30 days, sense probe. Original magnifications, ×375.