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. 2002 Dec;161(6):2179–2193. doi: 10.1016/s0002-9440(10)64495-1

Table 1.

Effects of Lisinopril on Urinary Protein Levels, Intraglomerular Protein and Inflammatory Cell Accumulation, α-SMA Expression, and Glomerulosclerosis

Group Proteinuria (mg/day) IgG (score) C3 (score) Alb (score) ED-1 OX-6 (MHC 11) α-SMA (score) Glomerulosclerosis (%)
(cells/glom section)
30-day RMR 225 ± 89* 1.30 ± 0.34* 0.73 ± 0.18* 1.80 ± 0.38* 12.51 ± 2.73* 12.09 ± 4.04* 1.16 ± 0.46* 18.9 ± 9.5*
30-day RMR+ lisinopril 28 ± 8 0.36 ± 0.35 0.18 ± 0.17 0.30 ± 0.20 7.20 ± 1.65 5.96 ± 1.77 0.34 ± 0.26 1.5 ± 2.3
30-day control 27 ± 5 0.26 ± 0.12 0.03 ± 0.05 0.19 ± 0.07 2.93 ± 0.70 3.09 ± 0.87 0 1.05 ± 0.8

*, P < 0.01 versus control;

, P < 0.01 versus RMR at 30 days.