Table 2.
Calf no.* | PID | Macroscopic changes (score) | Other agents at necropsy | BRSV antigen (score)† | CD4+ T cells (score)‡ | CD8+ T cells (score)‡ | ||
---|---|---|---|---|---|---|---|---|
Bronchi | Bronchioles | Alveoli | ||||||
IX-1 | 2 | 0 | U. | 0 | 0 | 0 | 1 | 1 |
IV-1 | 4 | 1 | U. | 0 | 0 | 0 | 1 | 1 |
IX-4 | 1 | — | 0 | 0 | 0 | 1 | 1 | |
IX-7 | 6 | 1 | M.d., U. | 0 | 0 | 0 | 1 | 1 |
XIV-1 | 1 | M.d. | 0 | 0 | 0 | 1 | 1 | |
IV-4 | 8 | 0 | M.d., | 0 | 0 | 0 | 1 | 1 |
IX-10 | 1 | M.d., M.b. | 0 | 0 | 0 | 1 | 1 | |
IV-7 | 15 | 1 | M.d. | 0 | 0 | 0 | 1 | 1 |
*First part of the calf number refers to the experiment number; last part of the number is the individual calf number. The inoculum in experiment number IV consisted of lung wash fluid from an uninfected calf whereas uninfected fetal bovine lung cells were used for inoculum in experiments IX, XI, and XIV.
†The BRSV antigen score is the average of the score from the eight evaluated areas of the lungs.
‡The CD4+ and CD8+ scores are the average of a score obtained from the same three different areas of the lung.
U.: Ureaplasma; M.d.: Mycoplasma dispar; M.b.: Mycoplasma bovirhinis.