Table 2.
Patient Characteristics According to Bone Scan Result
| Positive Scan (n = 60) |
Negative Scan (n = 354) |
|||||
|---|---|---|---|---|---|---|
| Variable | No. | % | No. | % | ||
| Positive surgical margin | 25 | 42 | 160 | 45 | ||
| Extracapsular extension | 32 | 53 | 171 | 48 | ||
| Seminal vesicle invasion | 25 | 41 | 98 | 28 | ||
| Lymph node metastases | 8 | 13 | 35 | 10 | ||
| Pathology Gleason sum | ||||||
| 2-6 | 16 | 27 | 91 | 26 | ||
| 7 | 22 | 37 | 164 | 46 | ||
| 8-10 | 22 | 37 | 99 | 28 | ||
| Median preoperative PSA, ng/mL | 18.4 | 14.7 | ||||
| Months from operation to BCR, median | 13.3 | 16.6 | ||||
| Median PSA doubling time, months | 5.2 | 6.6 | ||||
| Median trigger PSA, ng/mL | 58.0 | 5.8 | ||||
| Median years from BCR to first bone scan, median | 3.5 | 3.9 | ||||
| Median PSA velocity, ng/mL/mo | 1.4 | 0.12 | ||||
| Median PSA slope, log (ng/mL)/mo | 0.13 | 0.09 | ||||
Abbreviations: PSA, prostate-specific antigen; BCR, biochemical recurrence.