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. Author manuscript; available in PMC: 2008 Jan 2.
Published in final edited form as: Mol Cell Endocrinol. 2006 Oct 23;260-262:83–92. doi: 10.1016/j.mce.2006.06.012

Figure 2. Knobbed analogs of hFSH have low signaling activity in FSHR2 assays.

Figure 2

CHO cells that express the FSHR2 were incubated with increasing concentrations of hFSH and hFSH analogs containing knobs at α2 residues 42 or 48 as indicated on the figure. Cyclic AMP in the cells and medium was measured following a 20 minute incubation at 37°C. Values are means of triplicate incubations and the vertical lines extend to the limits of the SEM.