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. 2003 Jan;162(1):343–352. doi: 10.1016/S0002-9440(10)63825-4

Figure 5.

Figure 5.

Cytogenetic analysis of medulloblastoma cells derived from PARP-1/p53 double null mice. Metaphase chromosomes were prepared from primary medulloblastomas and stained with the telomeric FISH probe (D, F, H, J, and L) then counterstained with 4′,6′-diamidino-2-phenylindole (DAPI) (B, C, E, G, I, and K). A: Summary of chromosomal aberrations in primary medulloblastoma cells. RL, Robertsonian-like fusions; Dic, dicentric chromosomes. Radial chromosomes include triradial and quadriradial chromosomes. Representative metaphase spread from medulloblastoma cells is shown in (B) and chromosomal abnormalities include Robertsonian-like fusions (C and D), chromosomal break (E and F), fragmentations (G–J), triradial (I and J), and quadriradial (K and L) chromosomes.