Table 1.
BAI1 Expression and Genetic Status of Glioma Cell Lines 9
| Cell line | BAI1 mRNA (RT-PCR) | BAI1 Protein Western | TP53 Status codon (a.a change) | p14 Status codon (a.a change) | p16 Status codon (a.a change) |
|---|---|---|---|---|---|
| Normal brain (n = 5) | + | + | WT/WT | WT | WT |
| SF767 | + | − | WT/WT | WT | WT |
| LN-443 | + | − | WT/WT | del | del |
| LN-444 | + | − | WT/WT | del | del |
| LN-464 | + | − | 113/113 (F→S) | WT | WT |
| SF188 | + | − | 266/266 (G→E) | WT | WT |
| LN-Z308 | + | − | Null/null | WT | WT |
| U138MG | + | − | 213/213 (R→Q) | del | del |
| LN-401 | + | − | 215/215 (S→R) | del | del |
| LN-827 | − | − | WT/E56 stop | del | del |
| D247MG | − | − | WT/WT | del | del |
| U87MG | − | − | WT/WT | del | del |
| LN-319 | − | − | 175/175 | WT | WT |
| LN-235 | − | − | 176/176 (C→S) | WT | WT |
| U373MG | − | − | 273/273 (R→H) | WT | WT |
| LN-405 | − | − | 282/282 (R→W) | WT | WT |
| LN-229 | − | − | 98/98 (P→K) | del | del |
| LN-71 | − | − | 146/146 (W→stop) | del | del |
| LN-428 | − | − | 173 (V→M)/ | del | del |
| 282(R→W) | |||||
| LN-427 | − | − | 176/176 (C→S) | del | del |
| LN-340 | − | − | 181/181 (R→P) | del | del |
| U118MG | − | − | 213/213 (R→Q) | del | del |
| T98G | − | − | 237/237 (M→I) | del | del |
| HS683 | − | − | 248/248 (R→Q) | del | del |
| U251MG | − | − | 273/273 (R→H) | del | del |
| LN-432 | − | − | n.d. | n.d. | n.d. |
| LN-462 | − | − | n.d. | n.d. | n.d. |
| LN-702 | − | − | n.d. | n.d. | n.d. |
| LN-963 | − | − | n.d. | n.d. | n.d. |
wt, wild type; del, deleted; n.d., not determined.