Table 2.
Quantitation and Morphology of CCR8+ Cells in Cases with a Variety of Neurological Disorders and in Control Brain Sections
| Diagnosis | Number of cases | Gender, M:F | Median age | Number of lesions | Mean number of CCR8+ cells/mm2 | Mean number of CD68+ cells/mm2 | Morphology of CCR8+ cells |
|---|---|---|---|---|---|---|---|
| Rasmussen’s encephalitis | 1 | 0:1 | 13 | 1 | 0 | 809 | – |
| Neurosarcoidosis | 2 | 0:2 | 28 | 3 | 0 | 657 | – |
| PML | 1 | 0:1 | 79 | 2 | 468 | 805 | Microglia and macrophages |
| HSV encephalitis | 3 | 2:1 | 39 | 6 | 111 | 746 | Microglia |
| Rabies encephalitis | 2 | 2:0 | 10 | 2 | 25 | 1041 | Microglia |
| Cerebral toxoplasmosis | 1 | 0:1 | 30 | 2 | 280 | 683 | Microglia nodules |
| Cerebral malaria | 1 | 1:0 | na | 1 | 0 | 246 | – |
| Ischemic stroke | 7 | 4:3 | 66 | 10 | 856 | 1342 | Macrophages |
| Status epilepticus, posttreatment for malignant lymphoma complicated by cerebral toxoplasmosis and infarction | 1 | 1:0 | 62 | 1 | 963 | 1625 | Microglia and macrophages |
| Chronic encephalitis of undetermined etiology | 2 | 1:1 | 58 | 3 | 0 | 675 | – |
| Cerebral lymphoma | 1 | F | 87 | 2 | 0 | 469 | |
| Cerebral lymphoma complicated by acute and subacute infarction | 1 | F | 36 | 1 | 455 | 1059 | Microglia |
| Senile changes of the Alzheimer’s type | 8 | 3:5 | 78 | 9 | 0 | 79 | – |
| Control | 3 | 1:2 | 63 | 13 | 0 | 132 | – |
PML, progressive multifocal leukoencephalopathy; HSV, herpes simplex virus; na, not available.