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IHC Staining Pattern in Carriers of a Pathogenic Mutation
| IHC | MMR | MLH1 | MSH2 | MSH6 |
|---|---|---|---|---|
| 1+/2+/6+ | 3 (14%) | 1 (25%) | ||
| 1−/2+/6+ | 10 (48%) | |||
| 1+/2−/6+ | ||||
| 1+/2+/6− | 1 (8%) | 3 (75%) | ||
| 1−/2+/6− | 5 (24%) | |||
| 1+/2−/6− | 11 (92%) | |||
| 1−/2−/6+ | ||||
| 1−/2−/6− | 3 (14%) | |||
| Total | 21 | 12 | 4 |
1, MLH1; 2, MSH2; 6, MSH6; +, nuclear staining; −, no nuclear staining.
