Figure 5.
Array transcript data and protein validation studies of select proliferation markers. A: Up-regulation of TOP2A in ACC. Transcript data for three probe sets (light gray = 40145_at, medium gray = 904_s_at, and dark gray = 1592_at) the adrenocortical cohort and two representative tissue cores that show high- and low-level immunoreactivity for TOP2A. B: Up-regulation of Ki-67 in ACC. Transcript data (419_at) for the adrenocortical cohort and two representative tissue cores that show high and moderate levels of mib-1 immunoreactivity.