Table 1.
Ghrelin Expression in Fetal and Infant Thyroid Tissue
| No. | Sex | Age | Cause of death/associated disease | Ghrelin | |
|---|---|---|---|---|---|
| IHC | In situ hybridization | ||||
| 7122 | M/F* | 8 weeks† | Voluntary abortion | +++ | +++ |
| 13099 | na | 10 weeks† | Voluntary abortion | +++ | +++ |
| 6286 | na | 11 weeks† | Voluntary abortion | ++ | ++ |
| 6120 | na | 11 weeks† | Voluntary abortion | ++ | + |
| A36 | na | 12 weeks† | Voluntary abortion | +++ | na |
| 2542 | M | 13 weeks† | IUFD (placental abruption) | +++ | na |
| 867 | F | 14 weeks† | Elective abortion | ++ | + |
| 7727 | F | 16 weeks† | IUFD (osteogenesis imperfecta) | + | − |
| 6433 | M | 18 weeks† | Elective abortion | +++ | ++ |
| 11370 | M | 19 weeks† | Elective abortion | + | + |
| 11372 | F | 20 weeks† | Elective abortion | ++ | + |
| 6081 | M | 22 weeks† | IUFD (placental failure) | ++ | na |
| A3 | M | 25 weeks† | Elective abortion | ++ | + |
| A42 | M | 36 weeks† | IUFD (placental failure) | ++ | ++ |
| A5 | F | 38 weeks† | IUFD (hypoxia) | + | + |
| 2332 | M | 10 years | Follicular adenoma | − | − |
| 350380 | F | 10 years | Papillary carcinoma | − | − |
| 6549 | F | 11 years | Nodular goiter | − | − |
| 5509 | F | 13 years | Papillary carcinoma | − | − |
M, male; F, female; *, twins; na, not available;
†, gestational age; IUFD, intrauterine fetal death; IHC, immunohistochemistry; +, positive in less than 25% of tumor cells; ++, positive in 25 to 50% of tumor cells; +++, positive in more than 50% of tumor cells.