Table 4.

Cytokine levels are correlated to AP-1 expression

Biological markers	AP-1 negative (n = 34)		AP-1 positive (n = 69)		P
IL-1β	1.4	(0–11.5)	3.2	(0–260)	0.006
IL-2	0.4	(0–3.2)	1.4	(0–11)	0.001
IL-4	1.1	(0–99.6)	2.7	(0–30.2)	NS
IL-6	12.6	(4.4–70.7)	19.7	(7.8–26,487)	0.001
IL-8	29.6	(0 -778)	115	(1.5–15,890)	0.003
IL-10	0.2	(0–2.6)	0.3	(0– 5.6)	0.004
IL-12 (p70)	1.8	(0 -17.2)	2.7	(0–7.3)	0.044
IL-13	4.2	(3.0–7.2)	4.2	(3.4–394)	NS
G-CSF	17.2	(5.3–87.3)	18.5	(7.1–110)	NS
IFN-γ	25.4	(15.5–55.5)	28.7	(17.1–1,279)	0.002
MCP-1	54.6	(0–1,208)	148	(14.7–37,117)	0.001
MIP-1β	503	(87.2–8,778)	563	(42.6–14,439)	NS
TNF-α	6.9	(6.1–10.9)	7.8	(5.8–121)	0.002

Values are expressed as median (range; fg/μg). AP, activator protein; G-CSF, granulocyte colony-stimulating factor; IL, interleukin; IFN, interferon; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; NS, not significant; TNF, tumour necrosis factor.