Table 3.
Risk of second primary cancer by age at first primary male breast cancer diagnosis
| Age (years) | |||||||||||||||
| Cancer site | <60 | 60 to 69 | ≥70 | ||||||||||||
| N | PERYR | OBS | EXP | SIR (95 percent CI) | N | PERYR | OBS | EXP | SIR (95 percent CI) | N | PERYR | OBS | EXP | SIR (95 percent CI) | |
| All, breast included | 618 | 2,912.85 | 41 | 28.08 | 1.42 (1.02–1.94) | 547 | 2,681.23 | 89 | 72.35 | 1.24 (1.00–1.53) | 761 | 2,866.01 | 91 | 89.99 | 1.01 (0.81–1.24) |
| All, breast excluded | 618 | 2,929.25 | 36 | 28.29 | 1.24 (0.86–1.72) | 547 | 2,716.56 | 80 | 73.08 | 1.11 (0.88–1.38) | 761 | 2,883.83 | 85 | 90.26 | 0.94 (0.75–1.16) |
| Prostate | 618 | 2,982.99 | 15 | 8.41 | 1.78 (1.00–2.94) | 547 | 2,826.47 | 27 | 29.32 | 0.92 (0.61–1.34) | 761 | 2,994.29 | 27 | 34.56 | 0.78 (0.51–1.14) |
| Second breast | 605 | 2,992.73 | 5 | 0.06 | 81.38 (26.42–189.92) | 543 | 2,871.22 | 9 | 0.14 | 64.23 (29.37–121.92) | 758 | 3,083.94 | 6 | 0.18 | 32.98 (12.09–71.68) |
| Colorectal | 618 | 3,047.87 | 3 | 3.11 | 0.96 (0.20–2.82) | 547 | 2,891.37 | 15 | 8.19 | 1.83 (1.03–3.02) | 761 | 3,086.25 | 8 | 11.34 | 0.71 (0.30–1.39) |
| Lung and bronchus | 618 | 3,053.53 | 3 | 5.15 | 0.58 (0.12–1.70) | 547 | 2,902.69 | 13 | 12.81 | 1.02 (0.54–1.74) | 761 | 3,109.52 | 7 | 14.80 | 0.47 (0.19–0.97) |
| Bladder | 618 | 3,041.90 | 3 | 1.62 | 1.85 (0.38–5.41) | 547 | 2,901.04 | 6 | 4.87 | 1.23 (0.45–2.68) | 761 | 3,088.07 | 11 | 6.97 | 1.58 (0.79–2.82) |
| Melanomaa | 419 | 2,166.33 | 3 | 1.09 | 2.74 (0.57–8.01) | 427 | 2,358.83 | 5 | 1.72 | 2.92 (0.95–6.80) | 686 | 2,445.95 | 6 | 1.89 | 3.18 (1.17–6.93) |
| Stomach | 618 | 3,054.70 | 0 | 0.66 | 0.00 (0.00–4.54) | 547 | 2,909.55 | 4 | 1.66 | 2.41 (0.66–6.16) | 761 | 3,110.18 | 6 | 2.42 | 2.48 (0.91–5.40) |
Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios.