Table 5.
Risk of second primary cancer by time after first primary male breast cancer
| <1 year | 1 to 5 years | >5 years | |||||||||||||
| Cancer site | N | PERYR | OBS | EXP | SIR (95 percent CI) | N | PERYR | OBS | EXP | SIR (95 percent CI) | N | PERYR | OBS | EXP | SIR (95 percent CI) |
| All, breast included | 1,926 | 1,653.87 | 42 | 57.12 | 0.74 (0.53–0.99) | 1,884 | 4332.66 | 88 | 101.51 | 0.87 (0.70–1.07) | 1,796 | 2,469.34 | 91 | 55.92 | 1.63 (1.31–2.00) |
| All, breast excluded | 1,926 | 1,655.89 | 38 | 57.09 | 0.67 (0.47–0.91) | 1,888 | 4359.60 | 81 | 101.92 | 0.79 (0.63–0.99) | 1,807 | 2,509.90 | 82 | 56.64 | 1.45 (1.15–1.80) |
| Prostate | 1,926 | 1,666.28 | 14 | 20.83 | 0.67 (0.37–1.13) | 1,912 | 4450.10 | 27 | 37.81 | 0.71 (0.47–1.04) | 1,885 | 2,683.08 | 28 | 21.89 | 1.28 (0.85–1.85) |
| Second breast | 1,926 | 1,654.10 | 4 | 0.11 | 34.90 (9.51–89.35) | 1,922 | 4478.09 | 7 | 0.21 | 33.77 (13.58–69.57) | 1,915 | 2,811.43 | 9 | 0.12 | 75.85 (34.68–143.99) |
| Colorectal | 1,926 | 1,670.38 | 5 | 6.23 | 0.80 (0.26–1.87) | 1,921 | 4524.94 | 11 | 11.66 | 0.94 (0.47–1.69) | 1,910 | 2,825.87 | 10 | 7.11 | 1.41 (0.67–2.59) |
| Lung and bronchus | 1,926 | 1,672.78 | 4 | 9.23 | 0.43 (0.12–1.11) | 1,922 | 4540.41 | 6 | 17.21 | 0.35 (0.13–0.76) | 1,916 | 2,848.25 | 13 | 10.82 | 1.20 (0.64–2.05) |
| Bladder | 1,926 | 1,671.12 | 4 | 3.73 | 1.07 (0.29–2.74) | 1,922 | 4534.16 | 4 | 6.97 | 0.57 (0.16–1.47) | 1,918 | 2,821.43 | 12 | 4.15 | 2.89 (1.49–5.05) |
| Melanomaa | 1,454 | 1,276.50 | 1 | 1.48 | 0.68 (0.02–3.77) | 1,453 | 3491.48 | 7 | 2.61 | 2.68 (1.08–5.53) | 1,446 | 2,199.81 | 6 | 1.45 | 4.15 (1.52–9.02) |
| Stomach | 1,926 | 1,672.98 | 2 | 1.30 | 1.54 (0.19–5.58) | 1,924 | 4545.53 | 4 | 2.43 | 1.65 (0.45–4.21) | 1,920 | 2,851.61 | 4 | 1.50 | 2.66 (0.72–6.81) |
| Age (years) | |||||||||||||||
| <60 | 618 | 531.05 | 6 | 5.85 | 1.02 (0.38–2.23) | 612 | 1445.16 | 12 | 12.41 | 0.89 (0.44–1.59) | 600 | 935.26 | 23 | 8.18 | 2.81 (1.78–4.22) |
| 60 to 69 | 547 | 491.85 | 7 | 18.38 | 0.38 (0.15–0.78) | 540 | 1329.22 | 36 | 35.41 | 1.04 (0.74–1.44) | 504 | 858.89 | 46 | 23.64 | 1.95 (1.42–2.60) |
| 70+ | 761 | 630.97 | 29 | 32.89 | 0.88 (0.59–1.27) | 732 | 1558.27 | 40 | 53.69 | 0.74 (0.53–1.01) | 692 | 675.19 | 22 | 24.10 | 0.91 (0.57–1.38) |
Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios.