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(A) Schematic representation of a small model substrate (EGS:mRNA) for M1 RNA and a M1GS RNA construct to which a target mRNA has hybridized. (B) Schematic representation of the substrates used in the study. The targeted sequences that bind to the guide sequences of the ribozymes are highlighted. The sites of cleavage by M1 and M1GS RNAs are marked with filled arrows.
