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. Author manuscript; available in PMC: 2007 Apr 11.
Published in final edited form as: Radiology. 2005 Mar;234(3):909–916. doi: 10.1148/radiol.2343031499

TABLE 2.

Reliability, Reproducibility, and Random Noise of Labeled Echo-planar MR Imaging Measurements Obtained with Different Pulsed ASL Methods

Brain Region and
Measurement Parameter*
DIPLOMA EPISTAR PICORE
Global brain
ICC 0.98 (0.94, 0.99) 0.98 (0.93, 0.99) 0.96 (0.88, 0.99)
WSC  <0.01 <0.01 <0.01
Noise  <0.02 <0.02 <0.04
Gray matter
ICC 0.96 (0.88, 0.99) 0.97 (0.90, 0.99) 0.94 (0.80, 0.98)
WSC  <0.01 <0.01 <0.01
Noise  <0.03 <0.03 <0.06
White matter
ICC 0.99 (0.97, 0.99) 0.99 (0.96, 0.99) 0.98 (0.93, 0.99)
WSC  <0.01 <0.01 <0.01
Noise  <0.01 <0.01 <0.02
*

Perfusion-weighted images were obtained by subtracting the labeled from the nonlabeled echo-planar imaging data. ICC, a measure of reliability; WSC, a measure of reproducibility; and random noise are indexes of total variability and vary between 0 and 1.

Numbers in parentheses are 95% confidence intervals.

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