TABLE 2.
Reliability, Reproducibility, and Random Noise of Labeled Echo-planar MR Imaging Measurements Obtained with Different Pulsed ASL Methods
Brain Region and Measurement Parameter* |
DIPLOMA | EPISTAR | PICORE |
---|---|---|---|
Global brain | |||
ICC† | 0.98 (0.94, 0.99) | 0.98 (0.93, 0.99) | 0.96 (0.88, 0.99) |
WSC | <0.01 | <0.01 | <0.01 |
Noise | <0.02 | <0.02 | <0.04 |
Gray matter | |||
ICC† | 0.96 (0.88, 0.99) | 0.97 (0.90, 0.99) | 0.94 (0.80, 0.98) |
WSC | <0.01 | <0.01 | <0.01 |
Noise | <0.03 | <0.03 | <0.06 |
White matter | |||
ICC† | 0.99 (0.97, 0.99) | 0.99 (0.96, 0.99) | 0.98 (0.93, 0.99) |
WSC | <0.01 | <0.01 | <0.01 |
Noise | <0.01 | <0.01 | <0.02 |
Perfusion-weighted images were obtained by subtracting the labeled from the nonlabeled echo-planar imaging data. ICC, a measure of reliability; WSC, a measure of reproducibility; and random noise are indexes of total variability and vary between 0 and 1.
Numbers in parentheses are 95% confidence intervals.