. Author manuscript; available in PMC: 2007 Apr 11.

Published in final edited form as: Magn Reson Med. 2003 Sep;50(3):474–482. doi: 10.1002/mrm.10572

Table 3.

Comparisons Between Unfiltered, Apodized, and DSM Filtered MRSI Data of MI and NAA of White Matter

	MI^a	ICC_MI^b	NAA^a	ICC_NAA^b
a. Normal subjects^c
No filter	13.3 ± 3.0	–	24.2 ± 4.8	–
Apodization	12.5 ± 2.7^e	0.54	23.3 ± 4.3^e	0.90
DSM	13.2 ± 2.8	0.98	24.2 ± 4.5	0.95
b. AD patients^d
No filter	13.3 ± 4.6	–	23.3 ± 5.8	–
Apodization	12.5 ± 4.0^e	0.79	22.2 ± 5.2^e	0.73
DSM	13.3 ± 4.4	0.95	23.2 ± 5.6	0.98

Mean metabolite intensity ± standard deviation.

ICC, intraclass correlation coefficients between filtered (apodization or DSM) and unfiltered data. An ICC of 1 reflects a perfect correlation, an ICC of 0.5 indicated no correlation.

MRSI data from 22 cognitive normal controls with a total of 14,218 spectra of white matter.

MRSI data from 25 patients with Alzheimer's disease with a total 11,777 spectra of white matter.

P < 0.001 for filtered versus unfiltered MRSI.