Figure 4. LPO activity varies with thiocyanate concentration and with pH.
An arithmetic model of LPO activity using the kinetic constants published by Pruitt et al. [31] calculated the expected LPO activity with [SCN−] between 0.0001 M and 0.01 M (left panel) at pH 7.0, pH 6.5 and pH 6.0. The right panel shows an expanded view between 0 and 0.5 mM (0.4 mM being the concentration found in human airway secretions).