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Binding energetics of Notch1 polypeptide variants. Shown are the differences in the ΔG ° (open), ΔH ° (cross-hatched) and TΔS ° (solid) between RAMANKPPD and the shorter Notch polypeptides. Values for Δ ΔG ° , Δ ΔH ° and TΔ ΔS ° are given at 30 ° C.
