Table 1.
Antimicrobial activity of T. brownii stem bark extracts
Extracts/drugs | Organisms tested | ||||||||||
S. aureus | P. mirabilis | S. typhi | E. coli | P. aeruginosa | B. anthracis | B. cereus | K. pneumoniae | C. albicans | C. neoformans | ||
PE | IZ | - | - | - | - | - | - | - | - | - | - |
AI | - | - | - | - | - | - | - | - | - | - | |
DM | IZ | - | 3.0 ± 1.0 | - | - | 5.0 ± 1.0 | 4.3 ± 0.6 | - | - | - | - |
AI | - | 0.25 | - | - | 0.37 | 0.24 | - | - | - | - | |
DM:M (1:1) | IZ | 7.3 ± 1.1 | 7.3 ± 0.6 | - | 6.0 ± 0.0 | - | 4.7 ± 0.6 | - | - | 5.3 ± 0.6 | 4.7 ± 0.6 |
AI | 0.52 | 0.61 | 0.50 | - | 0.26 | - | - | 0.36 | 0.33 | ||
M | IZ | 10.3 ± 0.6 | - | - | - | - | 13.3 ± 0.6 | 7.3 ± 1.1 | 7.3 ± 1.1 | 10.0 ± 0.0 | 6.5 ± 0.7 |
AI | 0.73 | - | - | - | - | 0.74 | 0.52 | 0.55 | 0.68 | 0.45 | |
Aqua | IZ | 11.3 ± 1.1 | - | - | - | 8.7 ± 0.6 | 13.0 ± 1.7 | 7.3 ± 1.1 | 9.3 ± 0.6 | 10.7 ± 0.6 | 11.7 ± 0.6 |
AI | 0.81 | - | - | - | 0.65 | 0.72 | 0.52 | 0.70 | 0.73 | 0.82 | |
Gent | IZ | 14.0 ± 0.0 | 12.0 ± 2.0 | 13.7 ± 1.1 | 12.0 ± 1.0 | 13.3 ± 1.1 | 18.0 ± 1.0 | 14.0 ± 1.0 | 13.3 ± 2.1 | - | - |
AI | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | - | - | |
Clotr | IZ | - | - | - | - | - | - | - | - | 14.7 ± 0.6 | 14.3 ± 0.6 |
AI | - | - | - | - | - | - | - | - | 1.00 | 1.00 |
The results are presented as inhibition zone diameters in mm. Each value represents mean ± SD (n = 3). Key: PE = petroleum ether extract; DM = dicloromethane extract; 1:1 D:M = 1:1 dicloromethane:methanol extract; M = methanol extract; Aqua = aqueous extract; Gent = gentamicin; Clotr = Clotrimazole.