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. 2007 Feb;170(2):490–496. doi: 10.2353/ajpath.2007.060594

Figure 5.

Figure 5

MPO activity in colonic tissue of water-treated controls (n = 8) or after 7 days of treatment with water in WT controls (n = 8) or 2.5% DSS in WT mice (n = 7), WT⇒WT, WT⇒iNOS−/−, iNOS−/−⇒WT reconstituted mice (n = 8 per group), and iNOS−/− mice (n = 7). Tissue concentrations were measured by the O-dianisidine method described in Materials and Methods. The change in absorbance was read at 460 nm in a spectrophotometer. MPO activity was expressed as the amount of enzyme necessary to produce a change in absorbance of 1.0 per minute per g of wet weight of tissue. Mean ± SEM. #P < 0.05 versus water-treated controls, *P < 0.05 versus DSS treated WT and WT⇒WT, and ‡P < 0.05 versus DSS-treated iNOS−/−/⇒WT mice.