Table 3.

Multivariate Models of Hyperglycemic Progression

	Model A: Progression from Added to Original IFG			Model B: Progression from Added IFG to Diabetes			Model C: Progression from Original IFG to Diabetes			Model D: Progression from Either Stage to Diabetes
	Odds Ratio	95% CI	p value	Odds Ratio	95% CI	p value	Odds Ratio	95% CI	p value	Odds Ratio	95% CI	p value
Progressed to Original IFG	--	--	--	3.11	2.43 – 3.98	<0.0001	--	--	--	--	--	--
Initially Added IFG	--	--	--	--	--	--	1.12	0.88 - 1.42	0.352	--	--	--
Initially Original IFG	--	--	--	--	--	--	--	--	--	1.61	1.12 – 2.32	0.010
Initial FPG in stage (per mg/dl)	1.08	1.05 – 1.12	<0.0001	1.08	1.04 – 1.13	0.0003	1.07	1.04 – 1.10	<0.0001	1.07	1.04 – 1.10	<0.0001
Age (per 10 Years)	0.98	0.93 – 1.02	0.311	0.92	0.86 – 0.99	0.020	0.92	0.87 – 0.98	0.015	0.92	0.88 – 0.97	0.002
Female Sex	1.05	0.87 – 1.28	0.611	1.47	1.11 – 1.93	0.007	1.33	1.02 – 1.72	0.032	1.44	1.17 – 1.77	0.781
History of CVD	1.28	1.05 – 1.55	0.013	0.90	0.68 – 1.19	0.455	0.99	0.76 – 1.30	0.959	1.03	0.83 – 1.28	0.781
Current Smoker	0.99	0.80 – 1.23	0.944	1.51	1.15 – 1.99	0.003	1.17	0.89 – 1.53	0.255	1.24	1.00 – 1.54	0.047
BMI (per kg/m2)	1.03	1.02 – 1.05	<0.0001	1.04	1.02 – 1.06	<0.0001	1.03	1.02 – 1.05	<0.0001	1.04	1.03 – 1.06	<0.0001
Systolic BP (per 5mmHg)	1.04	1.00 – 1.08	0.066	1.10	1.04 – 1.16	<0.0001	1.08	1.03 – 1.14	0.001	1.09	1.05 – 1.14	<0.0001
HDL-C (per 5mg/dl)	0.93	0.89 – 0.96	0.0001	0.88	0.83 – 0.93	<0.0001	0.88	0.84 – 0.93	<0.0001	0.87	0.84 – 0.91	<0.0001
LDL-C (per 5mg/dl)	1.01	0.99 – 1.02	0.340	0.97	0.95 – 0.99	0.003	0.99	0.97 – 1.01	0.411	1.02	0.97 – 1.00	0.030
Triglycerides (per 50mg/dl)	1.01	1.00 – 1.02	0.002	1.01	1.00 – 1.02	0.026	1.03	1.01 – 1.04	0.0003	1.01	1.01 – 1.02	0.001