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. Author manuscript; available in PMC: 2007 Apr 12.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3492–3502.

Figure 7.

Figure 7

(A) Clinical course of acute anterior uveitis after the intracameral injection of an anti-Crry mAb (dashed curve); rats treated with 35 U of CVF 24 hours before antibody injection (solid line). Dashed straight line represents animals injected with irrelevant mAb, MOPC-21. Results show the mean ± SD from two experiments (n = 32 rats/group). (B) Histopathologic changes in the eye of Lewis rats after anti-Crry injection (a and b). At the peak of inflammation, iris and ciliary body (a) were severely inflamed (arrowheads). The anterior chamber (b) was also infiltrated by many cells, which were mainly PMNs (arrows). The cornea and the posterior segment of the eye were not involved. Intraocular inflammation did not develop in animals injected with CVF before antibody injection (c) and animals injected with anti-rat RT1A (d). Paraffin-embedded sections were stained with hematoxylin and eosin. Original magnification, (Ba, Bc, and Bd) × 100; (Bb) × 250.