Table 1.
Genotype | Treatment | [GSH] | [GSSG] | [GSH]/[GSSG] | Total Glutathione |
---|---|---|---|---|---|
WT | Veh | 34.8 ± 1.3 | 2.0 ± 0.1 | 17.7 ± 1.0 | 39.3 ± 1.2 |
DQ | 52.7 ± 2.5 * | 3.6 ± 0.5 | 15.5 ± 1.4 | 59.9 ± 3.4 * | |
N0 | Veh | 38.4 ± 1.9 | 2.5 ± 0.3 | 15.9 ± 1.4 | 43.5 ± 2.3 |
DQ | 24.4 ± 3.8 * | 7.4 ± 1.5 * | 4.1 ± 1.0 * | 39.2 ± 4.9 |
WT and NO cells were treated with 50 μM DQ or vehicle for 24-hr. Concentrations are expressed as nmole/mg protein. Values represent the mean ± SE of 6 independent experiments.
p < 0.05, compared to respective vehicle-treated group.