Table 2.
Induction of selected Nrf2-regulated genes following DQ treatmenta.
Gene | WT | N0 |
---|---|---|
Gclc | 2.1 ± 0.3 * | 0.7 ± 0.2 |
Gclm | 4.1 ± 0.3 * | 1.4 ± 0.4 |
Gsr1 | 2.1 ± 0.3 * | 1.0 ± 0.1 |
Prdx1 | 2.3 ± 0.2 * | 1.0 ± 0.1 |
WT and NO cells were treated with 50 μM DQ or vehicle for 13-hr. Data are expressed as fold-induction of gene transcripts (treated/vehicle). Values represent the mean ± SE of 3 independent experiments.
p < 0.05, compared to WT.