Figure 5. Reconstruction accuracy with the genetic (dotted and solid lines, as described in the Figure 4 legend) and without the genetic (dashed lines) information, using varying numbers of samples, and based on reduced heritability and a weak overall correlation structure compared with what we observed in the BXD network (see text for details).

(A) Accuracies of networks reconstructed with and without genetic information.

(B) Accuracies of subnetworks consisting only of those nodes in the top layer of the network.

(C) Accuracies of networks in which a true edge was counted as correct if the corresponding nodes were connected either directly or by a path involving two edges in the reconstructed network. It is clear the genetic data significantly enhance reconstruction accuracy.