Table 2.
Component outcomes by category of importance to patients (114 composite end points)
End point | Prevalence—No (%) |
---|---|
I. Death | 112 (98) |
All cause mortality | 43 (38) |
Mortality not otherwise defined | 32 (28) |
Cardiac death not otherwise defined | 13 (11) |
Cardiac death due to coronary heart disease not otherwise defined | 13 (11) |
Other fatal end points (n=9) | 24 (21) |
II. Critical | 18 (16) |
Large myocardial infarction | 14 (12) |
Stroke leaving permanent moderate deficit | 2 (2) |
Cardiac arrest followed by resuscitation manoeuvres | 2 (2) |
Dissecting or ruptured aortic aneurysm | 1 (1) |
Other critical end points (n=3) | 0 (0) |
III. Major | 95 (83) |
Non-fatal myocardial infarction | 83 (73) |
Stroke leaving permanent deficit, severity not defined | 16 (14) |
Coronary artery bypass grafting | 13 (11) |
Cerebrovascular event not otherwise defined | 13 (11) |
Other major end points (n=13) | 19 (17) |
IV. Moderate | 59 (52) |
Coronary revascularisation not otherwise specified | 22 (19) |
Coronary revascularisation—angioplasty/stenting | 12 (11) |
Non-fatal angina needing hospital admission | 11 (10) |
Hospital admission not otherwise specified | 5 (4) |
Other moderate end points (n=17) | 15 (13) |
V. Minor | 12 (11) |
Non-fatal angina, not defined | 7 (6) |
Non-fatal arrhythmias, not otherwise specified | 2 (2) |
Dyspnoea, not otherwise defined | 1 (1) |
Change in blood pressure | 1 (1) |
Other minor end points (n=10) | 2 (2) |