Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of HIV Env on activation marker expression
| No Env | IIIB Env | |
|---|---|---|
| CD4+ cells expressing, % | ||
| CD69 | 78.9 | 56.6 |
| HLA-DR | 23.5 | 12.9 |
| CD25 (IL2R-α) | 60.4 | 31.6 |
| CD4− cells expressing, % | ||
| CD69 | 59.2 | 61.8 |
| HLA-DR | 43.7 | 41.6 |
| CD25 (IL2R-α) | 33.3 | 22.2 |
PBMCs were exposed to control or IIIB Env expressing 293T cells and activated with anti-CD3. Expression of CD69 on day 1 and HLA-DR and CD25 on day 2 on CD4+ and CD4− T cells was determined using flow cytometry.
