Table 2.
LSMMG E. coli MG1655 genes down-regulated compared to the control in minimal MOPS medium.
| Gene | b# | Contran | Ave. Fold Change | Average p-value | Gene Product | Product Location | Present in S. Typhimurium |
| yaiN | b0357 | -2.28 | 0.0013 | orf, hypothetical protein | orthologue | ||
| copA | b0484 | -2.21 | 0.0012 | Cu-translocating P-type ATPase resistance pump | inner mem. | present | |
| renD | b0542 | yes | -2.02 | 0.0005 | orf, phage λ ren gene homolog | lysis | |
| emrE | b0543 | yes | -2.02 | 0.0001 | multidrug resistance pump, methylviologen resistance | inner mem. | orthologue |
| essD | b0554 | yes | -2.57 | 0.0001 | orf, phage lambda S lysis protein homolog | mem. lysis | |
| ybcS | b0555 | yes | -2.19 | 0.0001 | orf, bacteriophage lambda lysozyme homolog | wall lysis | orthologue |
| rzpD | b0556 | yes | -2.41 | 0.0001 | orf, bacteriophage lambda endopeptidase homolog | mem. disrpt. | orthologue |
| ybcH | b0567 | -3.17 | 0.0000 | orf, hypothetical protein | |||
| cusC | b0572 | yes | -2.57 | 0.0002 | outer mem. factor of CusABC Ag & Cu efflux system | outer mem. | orthologue |
| cusF | b0573 | yes | -4.06 | 0.0001 | Ag & Cu periplasmic binding protein, chaperone | periplasm | |
| cusB | b0574 | yes | -2.16 | 0.0001 | CusABC Ag & Cu efflux periplasmic fusion protein | periplasm | |
| cusA | b0575 | yes | -3.26 | 0.0001 | inner mem. factor of CusABC Ag & Cu transporter | inner mem. | orthologue |
| ybdF | b0579 | -2.47 | 0.0005 | orf, hypothetical protein | |||
| uspG | b0607 | -2.55 | 0.0003 | universal stress protein of UspA family, heat shock | cytoplasm | present | |
| yfiA | b2597 | -2.50 | 0.0007 | 30S ribosome stabilizing subunit, cold shock response | cytoplasm | present | |
| accB* | b3255 | -2.64 | 0.0001 | acetylCoA carboxylase, BCCP subunit; fatty acid bios. | cytoplasm | present | |
| cpxP | b3913/14 | -2.50 | 0.0002 | Cpx extracytoplasmic stress response repressor | periplasmic | present | |
| yjaH | b4001 | -2.32 | 0.0021 | orf, hypothetical protein | present | ||
| zraP | b4002 | -3.84 | 0.0000 | zinc binding periplasmic protein, responds to Zn & Pb | periplasm | present |
Ave. Fold Change and Average p-value columns are the averaged fold change in gene expression and p-values from the 3 MOPS minimal media functional genomic experiments.
*Gene product located in cytoplasm, but plays a role in membrane component regulation.
Underlined: associated or involved in membrane function, production or regulation.