Table 1.
Coenzyme Q10 in healthy female subjects before (day 0), during supplementation (day 14, day 28) with Sanomit Q10 (3 mg/kg/day), and 12 weeks after the last oral dose (day 112). Data are expressed as mean ± SDM (n=10). Statistical analysis was performed by ANOVA (LSD method; *p<0.05).
| CoQ10 supplementation | Day 0 | Day 14 | Day 28 | Day 112 |
|---|---|---|---|---|
| Plasma CoQ10 (µmol/L) | 1.02±0.30 | 3.93±1.29* | 4.11±1.08* | 1.12±0.30 |
| Plasma CoQ10 lipid-related (µmol Q10/mol chol) | 243±68 | 941±215* | 865±168* | 224±56 |
| Plasma CoQ10 redox-status (%Q10oxidized in Q10total) | 10.2±4.1 | 5.8±1.6* | 6.1±1.9* | 7.5±0.9* |
| Erythrocyte CoQ10 (pmol/cells x109) | 32.8±8.8 | 33.3±10.4 | 34.8±12.0 | 34.0±12.2 |
| Platelet CoQ10 (pmol/cells x109) | 190±57 | 374±224* | 441±156* | 256±57 |
| Platelet CoQ10 redox-status (%Q10oxidized in Q10total) | 19.8±6.6 | 14.0±4.6* | 14.9±3.8* | 17.8±5.4 |
| Comet-Assay (tail moment) | 1.47±0.23 | 1.48±0.13 | 1.29±0.13* | 1.24±0.17* |