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The effect of osteopontin on chondrocyte transglutaminase activity. Chondrocytes were incubated with various doses of milk osteopontin for 48 hours. Transglutaminase activity was measured in the cell layer using a standard radiometric assay, and was corrected for protein in the sample. Osteopontin significantly increased transglutaminase activity at all concentrations tested (n= 4, p < 0.01).
