Table 3.

Microbiology results

Cohorts of rats: Three groups of 6 rats were used for each route of inoculation	Positive blood culture (number of rats)*	Positive CSF culture (number of rats)*	Positive Middle ear swab (number of rats)*	Meningitis: confirmed with histology (number of rats)*
Intraperitoneal :
Cochleostomy only	2	0	0	0
Cochlear implantation	5	4	0	6
Acute implantation	2	0	0	0
Middle ear :
Cochleostomy only	2	0	6	0
Cochlear implantation	6	4	6	6
Acute implantation	5	3	5	2
Inner ear :
Cochleostomy only	1	0	3	0
Cochlear implantation	6	6	5	6
Acute implantation	0	0	0	0

Positive culture indicates that S. pneumoniae type 2 was isolated from the specimens when rats were euthanized.