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. 2007 Apr 4;8:11. doi: 10.1186/1471-2156-8-11

Table 3.

Predicted Amino Acid Sequence Comparison

Sry1 MEGHVKRPMN AFMVWSRGER RKLAQQNPSM QNSEISKHLG YQWKSLTEAE
Sry2    Q         M    GE  H L QQ  S  Q S    Q   YQ  S     
Sry3    H         M    GE  R L QQ  S  Q S    Q   YQ  S     
Sry3B1    H         M    GE  R L QQ  S  Q S    Q   YQ  S     
Sry3b    H         M    GE  R L QQ  S  Q S    Q   YQ  S     
Sry3C    H         M    GE  R L QQ  S  Q S    Q   YQ  S     
M. musculus    H         M    GE  H L QQ  S  Q T    Q   CR  S     
Human    H         I    DQ  R M LE  R  R S    Q   YQ  M     
Sry1 KRPFFQEAQR LKTLHREKYP NYKYQPHRRV KVPQRSYTLQ REVASTKLYN
Sry2  R       R  KTL            P                          
Sry3  R       R  KTL            T                          
Sry3B1  R       R  KTL            T                          
Sry3B  R       R  KTL            T                          
Sry3C  R       R  KTL            T                          
M.m  R       R  KIL                                       
Human  W       K  QAM                                       
Sry1 LLQWDNNLHT IIYGQDWARA AHQSSKNQKS IYLQPVDIPT GYPLQQKQQH
Sry2                                                    (--
Sry3
Sry3B1
Sry3B
Sry3C
Sry1 QQQQHVHLQQ QQQQQHQFH                                  
Sry2 ----------)                                           
Sry3       H                                               
Sry3B1       M  [Q]                                          
Sry3B       H  [Q]                                          
Sry3C       H                                                

Predicted amino acid sequence for each of the 6 copies of Sry found on the SHR Y chromosome compared to the amino acid sequence of Sry1. The HMG box (amino acids 5–73) is underlined and compared to Mus musculus and Human. Human (nm_003140.1) and mouse (nm_11564.1) sequences are from REFSEQ. Only differences are noted, (---) indicate amino acids that are deleted in Sry2, and [] indicate amino acids added in Sry3B and Sry3B1. Consensus rat sequence is in black and differences are bold.