Table 3.

Predicted Amino Acid Sequence Comparison

Sry1	MEGHVKRPMN AFMVWSRGER RKLAQQNPSM QNSEISKHLG YQWKSLTEAE
Sry2	Q         M    GE  H L QQ  S  Q S    Q   YQ  S
Sry3	H         M    GE  R L QQ  S  Q S    Q   YQ  S
Sry3B1	H         M    GE  R L QQ  S  Q S    Q   YQ  S
Sry3b	H         M    GE  R L QQ  S  Q S    Q   YQ  S
Sry3C	H         M    GE  R L QQ  S  Q S    Q   YQ  S
M. musculus	H         M    GE  H L QQ  S  Q T    Q   CR  S
Human	H         I    DQ  R M LE  R  R S    Q   YQ  M
Sry1	KRPFFQEAQR LKTLHREKYP NYKYQPHRRV KVPQRSYTLQ REVASTKLYN
Sry2	R       R  KTL            P
Sry3	R       R  KTL            T
Sry3B1	R       R  KTL            T
Sry3B	R       R  KTL            T
Sry3C	R       R  KTL            T
M.m	R       R  KIL
Human	W       K  QAM
Sry1	LLQWDNNLHT IIYGQDWARA AHQSSKNQKS IYLQPVDIPT GYPLQQKQQH
Sry2	(--
Sry3
Sry3B1
Sry3B
Sry3C
Sry1	QQQQHVHLQQ QQQQQHQFH
Sry2	----------)
Sry3	H
Sry3B1	M  [Q]
Sry3B	H  [Q]
Sry3C	H

Predicted amino acid sequence for each of the 6 copies of Sry found on the SHR Y chromosome compared to the amino acid sequence of Sry1. The HMG box (amino acids 5–73) is underlined and compared to Mus musculus and Human. Human (nm_003140.1) and mouse (nm_11564.1) sequences are from REFSEQ. Only differences are noted, (---) indicate amino acids that are deleted in Sry2, and [] indicate amino acids added in Sry3B and Sry3B1. Consensus rat sequence is in black and differences are bold.