Table 2. .
Spearman Correlation Coefficients[Note]
| Variable and Genotype |
tHcy | Folate | Riboflavin | Cobalamin |
| Folate: | −.44 | |||
| CC | −.38 | |||
| CT | −.45 | |||
| TT | −.58 | |||
| Riboflavin: | −.18 | .26 | ||
| CC | −.15 | .23 | ||
| CT | −.19 | .28 | ||
| TT | −.38 | .35 | ||
| Cobalamin: | −.24 | .16 | .20 | |
| CC | −.23 | .14 | .19 | |
| CT | −.25 | .19 | .22 | |
| TT | −.28 | .16 | .17 | |
| Vitamin B6: | −.24 | .39 | .35 | .18 |
| CC | −.20 | .35 | .34 | .16 |
| CT | −.24 | .41 | .36 | .20 |
| TT | −.38 | .47 | .43 | .17 |
Note.— Nonparametric Spearman correlation coefficients adjusted for sex, age, and study center are shown for the entire population (n=10,570) and separately for the MTHFR 677CC (n=5,433), 677CT (n=4,282), and 677TT (n=843) genotypes. All correlations were highly significant (P<.001).