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. 2007 Apr;8(4):309–315. doi: 10.1038/sj.embor.7400953

Table 3.

Illustrative criteria of seriousness, uncertainty and ambiguity (after Stirling et al, 2006)

Criteria of seriousness
Clear evidence of carcinogenicity, mutagenicity, or reprotoxicity in components/residues
Clear evidence of virulent pathogens
Clear violation of risk-based concentration thresholds or standards
Criteria of uncertainty and ignorance
Scientifically founded doubts on theory
Scientific doubts on model sufficiency or applicability
Scientific doubts on data quality or applicability
Novel, unprecedented features of the product
Criteria of sociopolitical ambiguity
Divergent individual perceptions of risk
Institutional conflict between different agencies
Amplification effects in news media
Social/ethical concerns, distributional issues or political mobilization